Isotonix® Multivitamin Fifty Plus
$49.95
(Single Bottle) 45 Servings
FEATURED RECOMMENDATIONS
Primary Benefits
- Helps promote normal levels of vitamins and minerals in aging men and women
- Provides nutrients essential for numerous processes in the body
- Contains activated forms of select B-vitamins to help ensure optimal utilization by the body
- B Vitamins are essential for many key functions in the body
- Vitamins B1, B2, B3, and biotin participate in different aspects of energy production
- Vitamin B5 is involved in the Kreb’s cycle of energy production and is needed to make the neurotransmitter acetylcholine. B5 is also essential in producing, transporting, and releasing energy from fats
- Vitamin B6 is essential for amino acid metabolism
- Vitamin B12 and folic acid facilitate steps required for cell division
- Folic acid helps form building blocks of DNA, the body’s genetic information, and building blocks of RNA, needed for protein synthesis in all cells.
- Aids in red blood cell formation
- Involved in the metabolism of proteins, fats, and carbohydrates
- Necessary for proper functioning of the nervous system, bone marrow and intestinal tract (B-vitamin deficiencies appear in these tissues first)
- Helps support brain health/cognitive health
- Helps maintain normal production of neurotransmitters
- Promotes/supports a healthy nervous system
- Supports a healthy heart
- Promotes cardiovascular health
- Supports healthy vision and eyes
- Supports healthy immune functions
- Supports skeletal and muscle health
- Supports healthy teeth and gums
- Provides a strong antioxidant defense

Product Classifications
Vegetarian - This product is vegetarian
Isotonic-Capable Drinkable Supplements - Easy-to-swallow supplements in liquid form are immediately available to the body for absorption
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity
Why Choose Isotonix Multivitamin Fifty Plus?
Adequate nutrition during the golden years has its challenges. As we age our bodies become less efficient at absorbing crucial nutrients, so it's important to be sure we’re getting the right vitamins and minerals. A good way to make sure you get all the nutrients you need is by taking a daily multivitamin supplement. Although a healthy diet is crucial to getting the nutrients your body needs, as we mature we often experience smaller appetites, loss of taste, dietary restrictions due to medical problems and stress can still impact our food choices and food quality, which can impede us from achieving our optimal nutrient intake via food alone.
People over 50 should take special care that they are getting enough B12 – found naturally in meats, fish, eggs and dairy products, along with folate – found in animal products and leafy vegetables. These are nutrients that the body absorbs less of as you get older. Getting enough B12 and folate supports the formation of red blood cells and promotes healthy nerve function. Adequate intake of B12 and folate can also support liver, heart and cognitive health.*
Vitamin C is an antioxidant, and wards off free radicals. Getting enough vitamin C is especially important as you get older because it supports immune health. Vitamin C supports healthy cholesterol levels in the blood and fights free radicals to support heathy eyes as we mature.*
Calcium and vitamin D are also critical nutrients to take in as you age, to help maintain bone strength; especially in women. In addition to needing added vitamins, aging adults need added minerals as well. Along with calcium, your aging body needs magnesium, chromium, potassium, zinc and many more to help you maintain good health.*
Making sure you get the proper nutrients may not turn back the clock, but it can help keep it wound up. Isotonix Multivitamin Fifty Plus is an isotonic-capable food supplement that has been specially formulated with a broad spectrum of nutrients that help support the health of adults 50+ and help keep your clock ticking efficiently. Isotonix Multivitamin Fifty Plus supplements dietary deficiencies and helps maintain normal metabolic functioning, essential to keeping you healthy as you age. *
Only Isotonix Multivitamin Fifty Plus contains a unique blend of complimentary vitamins and minerals with the superior delivery of Isotonix, which makes them easier to take for aging adults. Isotonix dietary supplements are a replica of the body’s own fluids such as tears, sweat and plasma. The body’s common osmotic pressure allows a consistent maintenance of body tissues. Isotonix Multivitamin Fifty Plus is readily available to our bodies due to its isotonic state.*
Isotonix dietary supplements are delivered in an isotonic liquid solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass efficiently into the small intestine and be rapidly delivered into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.*
Learn More
Isotonix® Delivery System

Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.
Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream.With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
FAQs
Why is taking a vitamin supplement important?
A vitamin may be broadly defined as a substance that is essential for the maintenance of normal metabolic function, but which is not produced in the body and therefore must be consumed from a source outside the body. They are necessary elements in the process of converting food to energy and in the growth and repair of body tissue. Reduction of vitamin levels over extended periods can result in vitamin deficiency. Deficiencies can be easily avoided by adequate vitamin intake to help fill the gaps in one’s diet.*
What separates Isotonix Multivitamin Fifty Plus from other multivitamins?
Isotonix Multivitamin Fifty Plus is formulated using the Isotonix Delivery System, which allows for nutrients to be delivered efficiently from your stomach to your intestines for maximum concentration. This means less nutritional value is lost, and you are getting a maximum benefit from this multivitamin.
Second, Isotonix Multivitamin Fifty Plus has been specifically formulated to serve aging adults. As we age our bodies tend to become less efficient at absorbing crucial nutrients, so it's important to be sure we’re getting the right vitamins and minerals, such as Folate as Quatrefolic® , vitamin C, zinc and vitamin B12.
What is the difference between Isotonix Multivitamin and Isotonix Multivitamin Fifty Plus?
Isotonix Multivitamin Fifty Plus has been specifically formulated to focus on specific nutrients that we need as we age. As you age, your body’s physiological needs, as well as your dietary intake changes. Isotonix Multivitamin Fifty Plus takes into consideration these physiological changes, the Recommended Dietary Reference Intakes (DRI) and the average American diet, to bring you a formula designed to help meet the changing health needs of aging adults.
Why doesn’t Isotonix Multivitamin Fifty Plus contain higher amounts of needed nutrients like Vitamin D3 and Calcium?
It is important to recognize that increased amounts of nutrients like Vitamin D3 and Calcium are essential to the health of aging inpiduals, however their addition to a multivitamin in higher amounts would not be properly rationed to the other ingredients in the multivitamin, essentially rendering the formulation less beneficial overall. Isotonix Multivitamin Fifty Plus pairs well with Isotonix Vitamin D3 with K2 and Isotonix Calcium Plus to get all the nutrients you need in the proper ratio.
How can vitamins A, C E and zinc help support my vision health as I age?
Vitamins A, C E and zinc as found in Isotonix Multivitamin Fifty Plus, are known to play a role in maintaining eye health and structure as you age. They also provide antioxidant protection.*
What type of vitamin E is in the Isotonix Multivitamin Fifty Plus?
The vitamin E in the Isotonix Multivitamin Fifty Plus is the natural, high activity d, 1-alpha-tocopherol. It has been converted to the acetate form to aid water solubility. This form of vitamin E, the natural form, is superior in terms of absorption and retention in the body. The natural form of alpha-tocopherol is known as d-alpha tocopherol, whereas the synthetic form is called dl-alpha tocopherol. The synthetic dl- form is the most common form found in dietary supplements, although many manufacturers, including Market America, have switched over to the more powerful (and expensive) natural d- form.
Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases. The US RDA's Human Nutrition Center on Aging claims vitamin B12 is the most important nutrient negatively affected by aging. Since vitamin B12 plays a critical role in promoting normal energy production and nervous system function, aging inpiduals need to make sure they are getting enough vitamin B12 on a daily basis.*
Why doesn’t Isotonix Multivitamin Fifty Plus contain copper?
Isotonix Multivitamin Fifty Plus was formulated to exclude copper to support the aging brain’s neurologic retention. Studies show a multivitamin formulated with additional zinc in the absence of copper is a formula that best supports the metabolic and neurologic needs of an aging brain.*
A six-year study of more than 3,700 people aged 65 or older showed that those who consumed at least 1.6 milligrams of copper a day, along with high levels of saturated and trans fats in their diets, added almost 20 years to their ages in terms of mental health. Many of those in the study with high copper levels took multivitamins containing the mineral.*
Who should take Isotonix Multivitamin Fifty Plus?
Everyone over the age of 50 would find it beneficial to enhance their diet with Isotonix Multivitamin Fifty Plus. Even when eating a balanced diet, it is difficult to consume the optimal amounts of vitamins and minerals each day. Numerous studies have been conducted on the importance of vitamins and minerals. One should supplement with a multivitamin to assure that their daily nutrient intake is balanced and powerful enough to ensure sufficient intake, allowing for the best health possible.*
What is the serving size for Isotonix Multivitamin Fifty Plus?
Adults ages 50 and up should take two (2) level capfuls mixed with four ounces (4 oz.) of water daily (once in the morning and once in the afternoon) or as directed by your healthcare provider.
Can I take Isotonix Multivitamin Fifty Plus with my prescriptions medications?
If you are currently using prescription drugs, have an ongoing medical condition, or if you are pregnant or breastfeeding, consult your healthcare provider before using this product.
What is the best way to store this product?
Keep Isotonix stored in a dry, cool place. If Isotonix are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator – but not in the fruit and vegetables area.
Key Ingredients
Scientific Studies
- Rasmussen HM1, Johnson EJ. Nutrients for the aging eye. Clin Interv Aging. 8:741-8, 2013.
- Etten, E., et al. 1,25-Dihydroxycholecalciferol: Endocrinology Meets the Immune System. Proceedings of the Nutrition Society. 61: 375-380, 2002.
- Lenton, Kevin J., et al. Vitamin C Augments Lymphocyte Glutathione in Subjects with Ascorbate Deficiency. American Journal of Clinical Nutrition. 77: 189 – 195, 2003.
- Rink, L. and Kirchner, H. Zinc-Altered Immune Function and Cytokine Production. Journal of Nutrition. 130: 1407S-1411S, 2000.
- Villamor, E. and Fawzi, W. Effects of Vitamin A Supplementation on Immune Response and Correlation with Clinical Outcomes. Clinical Microbiology Reviews. 18: 446-464, 2005.
- Haase H, Mocchegiani E, Rink L. Correlation between zinc status and immune function in the elderly. Biogerontology. 7(5-6):421-8., 2006. Review.
- Haase H, Rink L. The immune system and the impact of zinc during aging. Immun Ageing. 12;6:9, 2009.
- Deluca H et al. Vitamin D: its role and uses in immunology. FASEB Journal. 15(14):2579-2585, 2001.
- Hayes C et al. The immunological functions of the vitamin D endocrine system. Cellular and Molecular Biology. 49(2):277-300, 2003.
- Hall, S. and Greendale, G. The Relation of Dietary Vitamin C Intake to Bone Mineral Density: Results from the PEPI Study. Calcified Tissue International. 63: 183-189, 1998.
- Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. Washington, D.C.: National Academy Press; 2000.
- Henning S et al. Glutathione blood levels and other oxidant defense indexes in men fed diets low in vitamin C. Journal of Nutrition. 121:169-175, 1991.
- Johnston C et al. Vitamin C elevates red blood cell glutathione in healthy adults. American Journal of Clinical Nutrition. 58(1):103-105, 1993.
- Lenton K et al. Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency. American Journal of Clinical Nutrition. 77(1):189-195, 2003.
- Frei B et al. Ascorbate is an outstanding antioxidant in human blood plasma. Proceedings of the National Academy of Sciences USA. 86(16):6377-6381, 1989.
- Kirsch M et al. Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. Evidence that ascorbate acts by re-reducing substrate radicals produced by peroxynitrite. J Biol Chem. 275(22):16702-16708, 2000.
- Burton G et al. Vitamin E: Antioxidant activity, biokinetics, and bioavailability. Annual Review Nutrition. 10:357-382, 1992.
- Slyshenkov V et al. Pantothenic acid and pantothenol increase biosynthesis of glutathione by boosting cell energetics. FEBS Lett. 569(1-3):169-172, 2004.
TLS Product Reviews
Displaying reviews 1 - 5 of 25
05/17/2022
by BrianV
Love it
Just ordered , great taste, excellent product,
Response from Customer Service:
05/18/2022
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Multivitamin Fifty Plus! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
03/18/2022
by Anonymous
Multivitamin 50 plus
Love it!!
Response from Customer Service:
03/18/2022
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Multivitamin Fifty Plus! We are happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
12/02/2020
by AnnS
Wouldnt skip it ever
Great multivitamin! Tastes great and ca. Be mixed with other vitamins to make a complete supplement. Take it every morning and gice to my husband as well!
Response from Customer Service:
12/02/2020
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix Multivitamin Fifty Plus! We are happy to hear you are pleased with the product.
Thank you again!
The Product Information Team
10/08/2020
by DianaB
excellent nutrition
This is a very comprehensive product with everything I need as a more mature person. With the extra ingredients of enzymes, minerals, vitamins that we usually lose as we get older, it truly supplies and reenergizes for a feeling of cognizance, agility and general health. I take it daily. Very necessary to replenish those losses that occur starting at age 30!!
Response from Customer Service:
10/08/2020
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix Multivitamin Fifty Plus! We are happy to hear you are pleased with the product.
Thank you again!
The Product Information Team
07/25/2020
by RobertA
Awesome Product!
Love the ability to mix with other Isotonix products and drink. Tastes great and feel the the difference!!
Response from Customer Service:
07/27/2020
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix Multivitamin Fifty Plus! We are happy to hear you are pleased with the product.
Thank you again!
The Product Information Team