TLS® Trim Café

Gluten-Free - The finished product contains no detectable gluten (<10ppm gluten)

No Detectable GMOs - The finished product contains no detectable genetically-modified organisms

Vegan - The product is made without ingredients produced by or derived from animals

Drinkable Supplements - Easy-to-swallow supplements in liquid form are immediately available to the body for absorption

Quality Standards - GMP Operations and Standardized Ingredients

Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity

In your quest for lasting weight loss, find your slim with TLS® trim café, a dietary supplement. When used in conjunction with a regular exercise routine and balanced diet, trim café may promote an effective, multi-layered method to weight loss. trim café contains Columbian Arabica Coffee powder and GoTrim™ (Irvingia Gabonensis/African Mango). With GoTrim™, trim café provides three main mechanisms of action to promote healthy weight loss: fullness, appetite control and metabolic balance.*

Patented GoTrim™, is aclinically tested African Mango seed extract designed to support healthy weight loss and metabolic wellness. Based on clinical study results, GoTrim™ has successfully helped reduce body weight, body fat, and waist circumference over time.₁ It has also been shown in research studies to target the body in terms of satiety, metabolism, fat burning, fat production, and helping to maintain blood sugar balance.*₂

In the wide world of dietary supplements, TLS® trim café stacks up and can help support you on your weight loss journey. Simply pour our easy-to-use stick packs into a cup of hot water, stir and sip.* If you prefer your trim cafe´ cold, pour over ice.

Sources:

1. Ngondi, J., Etoundi, B., Nyangono, C., Mbofung, C., and Oben, J. (2009) IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation. Lipids in Health and Disease. 8(1-7)
2. Abedon, B. (2012). WellTrim®iG (IGOB131®) African Mango Extract is a Comprehensive Weight Management Ingredient [White Paper]. Retrieved June 15, 2017

GoTrim™ (IGOB131®) African Mango (Irvingia gabonensis) Seed Extract: 300 mg

GoTrim is a clinically studied extract of African mango, also known as Irvingia gambogia. African mango trees grow throughout farms and tropical forests of Central and Western Africa. This botanical ingredient is a traditional West African culinary fruit kernel in which the mucilage (a glycoprotein) is used to make traditional soups, such as Ogbono. GoTrim™ is the authentic, patented, clinically tested irvingia seed extract for weight loss and metabolic wellness. One of GoTrim’s mechanisms of action is supporting leptin sensitivity.*

Leptin is a hormone involved with hunger signals. Research has shown leptin levels to be elevated in those who are overweight. Irvingia gabonensis supports leptin in its ability to enter the brain and signal the stomach that it is full.*

Studies have shown Irvingia gabonensis also supports levels of the hormone adiponectin, a hormone closely related to glucose regulation/insulin sensitivity. Insulin helps the body store glucose correctly. This helps maintain normal blood sugar levels and insulin activity. Adiponectin has been associated with maintaining normal insulin sensitivity, which can support long-term metabolic health and overall weight loss. Adiponectin has also been shown to inhibit adipocytes (fat cells) from differentiating and multiplying, support fat burning and to support healthy endothelial function. Adiponectin levels are are generally related to body fat percentage; the greater the levels of adiponectin, the lower the percentage of fat.*

Additionally, the body’s fat cells store excess fat in a form that is easily packed away. Irvingia gabonensis acts upon one of the enzymes, glycerol-3-phosphate dehydrogenase, which helps form this stored fat. By supporting leptin sensitivity and healthy levels of adiponectin, Irvingia has the potential to help control hunger, help maintain normal blood sugar balance and promote thermogenesis–all important components of the metabolic rate. There are two published human clinical studies that have shown effects of Irvingia gabonensis for areas including appetite control, satiety, thermogenesis, weight management and metabolic wellness. Significant improvements in weight management and metabolic wellness variables occurred in both studies.*⁺

GoTrim™ is a trademark of Icon Group, LLC. IGOB131® is a trademark of Gateway Health Alliances, Inc. and is protected under U.S. Patent 7,537,790.

⁺The average person using 300 mg of GoTrim™, eating sensibly and exercising regularly, can expect to lose up to 2 pounds per week and 4.1% body fat percentage lost over a 10 week period of time.

• Bray G and York D. Clinical review 90: Leptin and clinical medicine: a new piece in the puzzle of obesity. Journal of Clinical Endocrinology and Metabolism. 82(9):2771-6, 1997.
• Cohen P, et al. Selective deletion of leptin receptor in neurons leads to obesity. Journal of Clinical Investigation. 108(8):1113-21, 2001. 
• Flegal K et al. Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 303(3):235-241, 2010.
• Friedman JM. The function of leptin in nutrition, weight, and physiology. Nutrition Reviews. 60(10 Pt 2):S1-14; discussion S68-84, 85-7, 2002. Review.
• Gil-Campos M, et al. Adiponectin, the missing link in insulin resistance and obesity. Clinical Nutrition. 23(5):963-74, 2004. Review.
• Ngondi J et al. Effect of Irvingia gabonensis kernel oil on blood and liver lipids on lean and overweight rats. Journal of Food Technology. 3:592-4, 2005. 
• Ngondi J et al. The effect of Irvingia gabonensis seeds on body weight and blood lipids of obese subjects in Cameroon. Lipids in Health and Disease. 4:12, 2005. 
• Oben J et al. Inhibition of adipogenesis by Irvingia gabonensis seed extract (IGOB131) as mediated via down regulation of the PPAR gamma and leptin genes, and up-regulation of the adiponectin gene. Lipids in Health and Disease. 7(1):44, 2008. 
• Oben J et al. Irvingia gabonensis on body weight and bloods lipids in normolipidemic guinea pigs. Journal of Food Technology. 3: 472-474, 2005. 
• Qi Y et al. Adiponectin acts in the brain to decrease body weight. Nature Medicine. 10(5):524-9, 2004. 
• Sinha M. Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting. Journal of Clinical Investigation. 98(6):1277-82, 1996. 
• Swierczynski J et al. Enhanced glycerol 3-phosphate dehydrogenase activity in adipose tissue of obese humans. Molecular and Cellular Biochemistry. 254(1-2):55-9, 2003.